Introduction In modern analytical chemistry, precision and accuracy are everything . One of the most powerful techniques used in pharmaceutical, environmental, and mineral analysis is the following: High Performance Liquid Chromatography (HPLC) High-performance liquid chromatography is a technique used to separate, identify, and quantify chemical components in a mixture with high accuracy and reproducibility. From drug purity testing to mineral extract analysis, HPLC plays a critical role in quality control (QC) laboratories worldwide . What is HPLC? HPLC (High Performance Liquid Chromatography) is an advanced analytical technique used to separate components in a liquid sample based on their interaction with the following: Stationary phase (column material) Mobile phase (liquid solvent) Simple Definition: HPLC separates compounds in a mixture so we can detect, identify, and measure them individually . Principle of HPLC (How it Works) HPLC works o...